Alan Barbour Bio

Alan Barbour



Dr. Alan Barbour is a Professor of Medicine and Microbiology & Molecular Genetics in the School of Medicine and Professor of Ecology & Evolutionary Biology in the School of Biological Sciences at the University of California Irvine. He received his MD from Tufts School of Medicine in Boston and was an internal medicine resident at Dartmouth-Hitchcock Medical Center in Hanover. He subsequently completed training in Internal Medicine and the subspeciality of Infectious Disease at the University of Utah.


Dr. Barbour continued research on bacterial pathogenesis at the National Institutes of Health’s (NIH) Rocky Mountain Laboratories in Montana, where he co-discovered the cause of Lyme disease and became section chief of arthropod-borne diseases. From 1986 to 1996 he was at the University of Texas Health Science Center at San Antonio as Professor of Medicine and Microbiology and Chief of the Division of ID. From 2005 to 2014 he was the Director and Principal Investigator of the NIH-supported Pacific-Southwest Regional Center of Excellence for Biodefense and Emerging Infections. He has served on several editorial boards, as a Division Chair with the American Society for Microbiology, as member of scientific advisory boards, as chair of the university’s academic senate, and as chair and standing member of NIH and Veterans Administration study sections. His research has mainly been devoted to the pathogenesis, immunity, and genetics of the spirochetal infections relapsing fever and Lyme disease, but have also included other pathogens, including staphylococci and mechanisms of antibiotic resistance.


Dr. Barbour is a Collaborator on the grant. His main role will be to provide advice and guidance to the Network’s investigators. He is willing to provide expertise on and resources for the development of immunodiagnostic assays, genome-wide expression profiling of host responses, and direct genotyping of Lyme disease agents in ticks and mammalian specimens.